Product Datasheet
PXN Antibody
Catalog Number: 37012
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: F5GZ78
NCBI Gene ID: 5829
Gene Accssion: NP_002850
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human Paxillin
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- FLJ16691; PAXI; Paxillin; PXN
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PXN protein.
- Background:
- This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).
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