Product Datasheet
GRIN2C Antibody
Catalog Number: 37003
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q14957
NCBI Gene ID: 2905
Gene Accssion: NP_000826
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- appl_detail:
- Immunohistochemistry: 1:100-1:300
- other_names:
- NR2C; GluN2C; NMDAR2C
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total GRIN2C protein.
- Background:
- N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).
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