Product Datasheet
GRIN1 Antibody
Catalog Number: 37001
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q05586
NCBI Gene ID: 2902
Gene Accssion: NP_000823
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human glutamate receptor, ionotropic, N-methyl D-aspartate 1
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- NR1; MRD8; GluN1; NMDA1; NMDAR1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total GRIN1 protein.
- Background:
- The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
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