Product Datasheet
CDH2 Antibody
Catalog Number: 36995
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P19022
NCBI Gene ID: 1000
Gene Accssion: NP_001783
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human cadherin 2, type 1, N-cadherin (neuronal)
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- CDHN; NCAD; CD325; CDw325
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CDH2 protein.
- Background:
- This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.?
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