Product Datasheet
MTOR Antibody
Catalog Number: 36991
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P42345
NCBI Gene ID: 2475
Gene Accssion: NP_004949
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human mechanistic target of rapamycin (serine/threonine kinase)
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- FRAP; FRAP1; FRAP2; RAFT1; RAPT1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MTOR protein.
- Background:
- The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
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