Product Datasheet
MIDN Antibody
Catalog Number: 36984
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q504T8
NCBI Gene ID: 90007
Gene Accssion: NP_796375
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human Midnolin
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- DKFZp547M072; MIDN; Midnolin
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MIDN protein.
- Background:
- Expression of the?midnolin?gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. The?midnolin?encodes a protein of 508 amino acids (aa), which contains a Ubiquitin-like domain. The intracellular distribution of the?midnolin?was studied by using?midnolin-green fluorescent protein (GFP) fusion proteins.?Midnolin?was found to be localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the?midnolin.?May be involved in regulation of genes related to neurogenesis in the nucleolus
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