Product Datasheet
MC3R Antibody
Catalog Number: 36971
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P41968
NCBI Gene ID: 4159
Gene Accssion: NP_063941
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human melanocortin 3 receptor
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- MC3; OB20; OQTL; BMIQ9; MC3-R
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MC3R protein.
- Background:
- This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
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