Product Datasheet
MC2R Antibody
Catalog Number: 36970
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q01718
NCBI Gene ID: 4158
Gene Accssion: NP_000520
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human Melanocortin 2 receptor (adrenocorticotropic hormone)
- appl_detail:
- Western blotting: 1:1000-1:5000
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MC2R protein.
- Background:
- MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
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