Product Datasheet
CCL8 Antibody
Catalog Number: 36968
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P80075
NCBI Gene ID: 6355
Gene Accssion: NP_005614
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human chemokine (C-C motif) ligand 8
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- HC14; MCP2; MCP-2; SCYA8; SCYA10
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CCL8 protein.
- Background:
- This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [
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