Product Datasheet
MAFF Antibody
Catalog Number: 36964
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9ULX9
NCBI Gene ID: 23764
Gene Accssion: NP_036455
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human v-maf musculoaponeurotic fibrosarcoma oncogene homolog F
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- U-MAF; hMafF
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MAFF protein.
- Background:
- The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene.
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