Product Datasheet
LRIG3 Antibody
Catalog Number: 36955
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q6UXM1
NCBI Gene ID: 121227
Gene Accssion: NP_700356
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human leucine-rich repeats and immunoglobulin-like domains 3
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total LRIG3 protein.
- Background:
- Leucine-rich repeats and immunoglobulin-like domains 3 (Lrig3) was identified by microarray analysis among genes that show differential expression during gastrulation in Xenopus laevis.?Lrig3?was expressed in the neural plate and neural crest (NC) at neurula stages, and in NC derivatives and other dorsal structures during tailbud stages. A prominent consequence of the morpholino-induced inhibition of?Lrig3?expression was impaired NC formation, as revealed by the suppression of marker genes, including Slug, Sox9 and Foxd3.
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