Product Datasheet  
LRIG1 Antibody  
Catalog Number: 36954  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q96JA1
    NCBI Gene ID: 26018
    Gene Accssion: NP_056356
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human leucine-rich repeats and immunoglobulin-like domains 1
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:50-1:200
  • other_names：  
  • LIG1; LIG-1
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total LRIG1 protein.
  • Applications：  
  • IHC
  • Background：  
  • Leucine-rich repeats and immunoglobulin-like domains protein 1?is a?protein?that in humans is encoded by the?LRIG1?gene.?It encodes a?transmembrane protein?that has been shown to interact with receptor tyrosine kinases of the?EGFR-family?,?MET?and?RET. Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.



 
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