Product Datasheet
KLK5 Antibody
Catalog Number: 36941
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y337
NCBI Gene ID: 25818
Gene Accssion: NP_036559
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human kallikrein-related peptidase 5
- appl_detail:
- Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:100-1:300
- other_names:
- SCTE; KLKL2; KLK-L2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total KLK5 protein.
- Background:
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.?
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