Product Datasheet
IRS4 Antibody
Catalog Number: 36937
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O14654
NCBI Gene ID: 8471
Gene Accssion: NP_003595
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human insulin receptor substrate 4
- appl_detail:
- Immunohistochemistry: 1:20-1:100
- other_names:
- IRS-4; PY160
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total IRS4 protein.
- Background:
- IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation
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