Product Datasheet  
LILRB3 Antibody  
Catalog Number: 36936  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O75022
    NCBI Gene ID: 102725035
    Gene Accssion: NP_001074919
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:15-1:50
  • other_names：  
  • HL9; ILT5; LIR3; PIRB; CD85A; ILT-5; LIR-3; LILRA6
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total LILRB3 protein.
  • Applications：  
  • IHC
  • Background：  
  • This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.



 
© Signalway Biotechnology All Rights Reserved.