Product Datasheet
ING1 Antibody
Catalog Number: 36932
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UK53
NCBI Gene ID: 3621
Gene Accssion: NP_005528
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human inhibitor of growth family, member 1
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- p33; p47; p33ING1; p24ING1c; p33ING1b; p47ING1a
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ING1 protein.
- Background:
- This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
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