Product Datasheet
IGFBP7 Antibody
Catalog Number: 36930
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q16270
NCBI Gene ID: 3490
Gene Accssion: NP_001544
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human insulin-like growth factor binding protein 7
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:10-1:50
- other_names:
- AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total IGFBP7 protein.
- Background:
- This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm
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