Product Datasheet
HOXD11 Antibody
Catalog Number: 36925
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P31277
NCBI Gene ID: 3237
Gene Accssion: NP_067015
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human homeobox D11
- appl_detail:
- Western blotting: 1:1000-1:3000
- other_names:
- Hox-4.6; Hoxd-11
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HOXD11 protein.
- Background:
- This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis.?
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