Product Datasheet  
HCN2 Antibody  
Catalog Number: 36922  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q9UL51
    NCBI Gene ID: 610
    Gene Accssion: NP_001185
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human hyperpolarization activated cyclic nucleotide-gated potassium channel 2
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:50-1:200
  • other_names：  
  • BCNG2; HAC-1; BCNG-2
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total HCN2 protein.
  • Applications：  
  • IHC
  • Background：  
  • Hyperpolarization-activated cation channels of the HCN gene family, such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain. Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages.



 
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