Product Datasheet
GSK3B Antibody
Catalog Number: 36918
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P49841
NCBI Gene ID: 2932
Gene Accssion: NP_002084
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human glycogen synthase kinase 3 beta
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- GSK-3 beta; GSK3B; GSK3beta isoform
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total GSK3B protein.
- Background:
- The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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