Product Datasheet
TBX2 Antibody
Catalog Number: 36873
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q13207
NCBI Gene ID: 6909
Gene Accssion: NP_005985
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human T-box 2
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- FLJ10169; T-box 2; T-box protein 2; TBX2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TBX2 protein.
- Background:
- This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.
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