Product Datasheet
FOXE1 Antibody
Catalog Number: 36866
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O00358
NCBI Gene ID: 2304
Gene Accssion: NP_004464
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human forkhead box E1 (thyroid transcription factor 2)
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- TTF2; FOXE2; HFKH4; HFKL5; TITF2; TTF-2; FKHL15
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total FOXE1 protein.
- Background:
- This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.?
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