Product Datasheet
FPR2 Antibody
Catalog Number: 36856
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P25090
NCBI Gene ID: 2358
Gene Accssion: NP_001453
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human formyl peptide receptor 2
- appl_detail:
- Immunohistochemistry: 1:20-1:100
- other_names:
- ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total FPR2 protein.
- Background:
- Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4
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