Product Datasheet
FOSB Antibody
Catalog Number: 36855
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P53539
NCBI Gene ID: 2354
Gene Accssion: NP_006723/P53539
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human FBJ murine osteosarcoma viral oncogene homolog B
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
- other_names:
- AP-1; G0S3; GOS3; GOSB
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total FOSB protein.
- Background:
- The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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