Product Datasheet  
FOSB Antibody  
Catalog Number: 36855  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P53539
    NCBI Gene ID: 2354
    Gene Accssion: NP_006723/P53539
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to residues near the C terminal of human FBJ murine osteosarcoma viral oncogene homolog B
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:50-1:200
  • other_names:  
  • AP-1; G0S3; GOS3; GOSB
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total FOSB protein.
  • Applications:  
  • WB IHC
  • Background:  
  • The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.



 
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