Product Datasheet
FBLN1 Antibody
Catalog Number: 36852
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P23142
NCBI Gene ID: 2192
Gene Accssion: NP_001987
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human fibulin 1
- appl_detail:
- Immunohistochemistry: 1:100-1:300
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total FBLN1 protein.
- Background:
- Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
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