Product Datasheet
EPHA1 Antibody
Catalog Number: 36844
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P21709
NCBI Gene ID: 2041
Gene Accssion: NP_005223
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human Ephrin type-A receptor 1
- appl_detail:
- Immunohistochemistry: 1:10-1:50
- other_names:
- EPH; EPHT; EPHT1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total EPHA1 protein.
- Background:
- This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
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