Product Datasheet
SFRP5 Antibody
Catalog Number: 36839
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q5T4F7
NCBI Gene ID: 6425
Gene Accssion: NP_003006
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human secreted frizzled-related protein 5
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SFRP5 protein.
- Background:
- Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas.
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