Product Datasheet
EDNRA Antibody
Catalog Number: 36835
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P25101
NCBI Gene ID: 1909
Gene Accssion: NP_001948
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human endothelin receptor type A
- other_names:
- ETA; ET-A; ETAR; ETRA; ETA-R; hET-AR
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total EDNRA protein.
- Background:
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.?
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