Product Datasheet
DVL2 Antibody
Catalog Number: 36830
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O14641
NCBI Gene ID: 1856
Gene Accssion: NP_004413
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human dishevelled segment polarity protein 2
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- Dishevelled-2; DSH homolog 2; DVL2;
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total DVL2 protein.
- Background:
- This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
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