Product Datasheet
SLC6A3 Antibody
Catalog Number: 36823
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q01959
NCBI Gene ID: 6531
Gene Accssion: NP_001035
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human solute carrier family 6 (neurotransmitter transporter), member 3
- appl_detail:
- Immunohistochemistry: 1:100-1:300
- other_names:
- DAT; DAT1; PKDYS
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SLC6A3 protein.
- Background:
- This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.
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