Product Datasheet
HRH3 Antibody
Catalog Number: 37632
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y5N1
NCBI Gene ID: 11255
Gene Accssion: NP_009163
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human histamine receptor H3
- appl_detail:
- Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200
- other_names:
- HH3R; GPCR97
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HRH3 protein.
- Background:
- Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
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