Product Datasheet
CYLD Antibody
Catalog Number: 37514
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NQC7
NCBI Gene ID: 1540
Gene Accssion: NP_056062
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human cylindromatosis (turban tumor syndrome)
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- EAC; MFT; SBS; TEM; BRSS; CDMT; MFT1; CYLD1; CYLDI; USPL2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CYLD protein.
- Background:
- This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.?
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