Product Datasheet
CUL4B Antibody
Catalog Number: 37513
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q13620
NCBI Gene ID: 8450
Gene Accssion: NP_001073341
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human cullin 4B
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- SFM2; MRXSC; MRXHF2; MRXS15
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CUL4B protein.
- Background:
- This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.?
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