Product Datasheet
EPHB3 Antibody
Catalog Number: 37140
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P54753
NCBI Gene ID: 2049
Gene Accssion: NP_004434
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human EPH receptor B3
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- ETK2; HEK2; TYRO6
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total EPHB3 protein.
- Background:
- Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members.
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