Product Datasheet
GRK1 Antibody
Catalog Number: 36915
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q15835
NCBI Gene ID: 6011
Gene Accssion: NP_002920
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human G protein-coupled receptor kinase 1
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- RK; RHOK; GPRK1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total GRK1 protein.
- Background:
- This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).
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