Product Datasheet
DPYSL4 Antibody
Catalog Number: 36805
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O14531
NCBI Gene ID: 10570
Gene Accssion: NP_006417
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human dihydropyrimidinase-like 4
- appl_detail:
- Western blotting: 1:500-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- CRMP3; DRP-4; ULIP4
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total DPYSL4 protein.
- Background:
- Collapsin response mediator protein 3 is an enzyme that in humans is encoded by the CRMP3 gene.It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.And plays a role in axon guidance, neuronal growth cone collapse and cell migration.Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1. Phosphorylated upon DNA damage, probably by ATM or ATR.
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