Product Datasheet
DPYSL2 Antibody
Catalog Number: 36804
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q16555
NCBI Gene ID: 1808
Gene Accssion: NP_001377
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human Collapsin response mediator protein 2
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- DRP2; N2A3; DPYSL2; DRP-2; ULIP2; CRMP-2; DHPRP2; ULIP-2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total DPYSL2 protein.
- Background:
- This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
© Signalway Biotechnology All Rights Reserved.