Product Datasheet
CLDN5 Antibody
Catalog Number: 36799
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O00501
NCBI Gene ID: 7122
Gene Accssion: NP_001124333
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human claudin 5
- appl_detail:
- Immunohistochemistry: 1:5-1:20
- other_names:
- AWAL; BEC1; TMVCF; CPETRL1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CLDN5 protein.
- Background:
- This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene
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