Product Datasheet
KRT10 Antibody
Catalog Number: 36795
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P13645
NCBI Gene ID: 3858
Gene Accssion: NP_000412
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human Keratin, type I cytoskeletal 10
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- BIE; EHK; K10; KPP; BCIE; CK10
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total KRT10 protein.
- Background:
- This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.
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