Product Datasheet
KRT14 Antibody
Catalog Number: 36794
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P02533
NCBI Gene ID: 3861
Gene Accssion: NP_000517
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human Keratin, type I cytoskeletal 14
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- K14; NFJ; CK14; EBS3; EBS4
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total KRT14 protein.
- Background:
- This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.
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