Product Datasheet
CCL6 Antibody
Catalog Number: 36780
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P55773
NCBI Gene ID: 6368
Gene Accssion: NP_033165
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human C-C motif chemokine 6
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- C10; Scya6; MRP-1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CCL6 protein.
- Background:
- In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, and can be greatly induced under conditions suitable for myeloid cell differentiation. It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF. Some low levels of gene expression also occur in certain cell lines of myeloid origin (e.g. the immature myeloid cell lines DA3 and 32D cl3, and the macrophage cell line P388D) that can also be greatly induced in culture with GM-CSF. However, in activated T cell lines, expression of CCL6 is greatly reduced.CCL6 can also be induced in the mouse lung by the cytokine interleukin 13
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