Product Datasheet
POU2AF1 Antibody
Catalog Number: 36775
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q16633
NCBI Gene ID: 5450
Gene Accssion: NP_006226
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human POU class 2 associating factor 1
- appl_detail:
- Immunohistochemistry: 1:10-1:50
- other_names:
- BOB1; OBF1; OCAB; OBF-1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total POU2AF1 protein.
- Background:
- POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene. POU2AF1 has been shown to interact with POU2F1 and SIAH1. POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene.Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It encourages the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is necessary for the response of B-cells to antigens and required for the formation of germinal centers.
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