Product Datasheet
AP1G1 Antibody
Catalog Number: 36741
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O43747
NCBI Gene ID: 164
Gene Accssion: NP_001025178
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human Adapter-related protein complex 1 subunit gamma-1
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- ADTG; CLAPG1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AP1G1 protein.
- Background:
- Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
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