Product Datasheet
CRADD Antibody
Catalog Number: 36713
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P78560
NCBI Gene ID: 8738
Gene Accssion: BC037905/P78560
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- MRT34; RAIDD
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CRADD protein.
- Background:
- The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
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