Product Datasheet
PYGM Antibody
Catalog Number: 36710
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P11217
NCBI Gene ID: 5837
Gene Accssion: BC126392/P11217
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human phosphorylase, glycogen, muscle
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:30-1:150
- other_names:
- Myophosphorylase; phosphorylase; glycogen;muscle
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PYGM protein.
- Background:
- This gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency), a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants.
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