Product Datasheet
PTPN7 Antibody
Catalog Number: 36706
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P35236
NCBI Gene ID: 5778
Gene Accssion: BC001746/P35236
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human protein tyrosine phosphatase, non-receptor type 7
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
- other_names:
- LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PTPN7 protein.
- Background:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities.
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