Product Datasheet
TMPRSS2 Antibody
Catalog Number: 36703
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O15393
NCBI Gene ID: 7113
Gene Accssion: BC051839/O15393
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human transmembrane protease, serine 2
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- PP9284; PRSS10
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TMPRSS2 protein.
- Background:
- This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue.?
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