Product Datasheet
PRR5 Antibody
Catalog Number: 36702
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P85299
NCBI Gene ID: 55615
Gene Accssion: BC016921/P85299
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- PP610; PROTOR1; PROTOR-1; FLJ20185k
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PRR5 protein.
- Background:
- This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms.
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