Product Datasheet
PLS3 Antibody
Catalog Number: 36696
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P13797
NCBI Gene ID: 5358
Gene Accssion: BC039049/P13797
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human plastin 3
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- BMND18; T-plastin
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PLS3 protein.
- Background:
- Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.).
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