Product Datasheet
PDGFRL Antibody
Catalog Number: 36686
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q15198
NCBI Gene ID: 5157
Gene Accssion: BC010927/Q15198
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human platelet-derived growth factor receptor-like
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- PDGRL; PRLTS
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PDGFRL protein.
- Background:
- This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.?
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